I tried iTunes first and although it worked, you couldn't put songs into folders. So all you had was about 170 songs one after the other and it was a nightmare to find what you wanted to listen to.
Using Nero, you can create folders and add songs to the folders. So if you call the folder the name of the artist or album etc, it acts the same as a CD changer. You select the folder (or artist) you want to listen to. It is far easier to find what you want. And as my daughter has Hairspray and High School Musical on, I don't have to listen to her stuff when I'm on my own!